Israel Diagnostics 2025: 90+ Startups Redefining the Future of Early Detection

Why it matters: Diagnostics is no longer just about lab results — it’s about AI, access, and actionable insights at the point of care. Israel, with its unique blend of deep-tech talent, strong clinical partnerships, and global-facing entrepreneurs, has become a diagnostics powerhouse.

Here’s a framework for how these startups stand out — and how they inspire others:

🔑 Framework for Diagnostic Leadership

1. AI at Scale – Leveraging computer vision and predictive analytics to turn images into clinical decisions.

2. Access Anywhere – Designing tools for homes, pharmacies, and rural clinics, not just hospitals.

3. Biomarker Breakthroughs – Translating biology (genomics, proteomics, host-response) into real-time signals.

4. Human-Centered Design – From fetal ultrasound at home to smartphone urinalysis, UX is core.

5. Global Partnerships – FDA clearances, EU rollouts, and pharma collaborations accelerate trust.

🖼 Imaging AI

Turning pixels into precise decisions

• Aidoc – radiology AI covering stroke, PE, ICH.

• Nanox.AI – CT-based risk models (liver, heart, bone).

• DiA Imaging – automated ultrasound measurements.

• UltraSight – AI-guided cardiac ultrasound (FDA-cleared).

• IMedis AI – QA for CT/MRI workflows.

• Magentiq Eye – AI for endoscopy (polyps).

• RealView Imaging – holography for interventional imaging.

• Arineta – cardiac CT systems.

• RSIP Vision – AI modules for surgical/diagnostic imaging.

• Theator – surgical video analytics.

• IntraVision – intraoperative analytics.

• MedyMatch – CT stroke detection pioneer.

• RealEyes – ophthalmic + radiology fusion.

• Subtle Medical Israel – AI imaging noise reduction.

Strategy Insight: Israeli imaging AI excels at narrow clinical validation with rapid FDA/EU clearance, then scaling through OEM/device partnerships.

🔬 Digital Pathology

From glass slides to AI-driven biomarkers

• Ibex Medical Analytics – leading pathology AI.

• Nucleai – spatial biomarker discovery.

• Imagene AI – H&E-based genomic surrogates.

• Scopio Labs – digital cell morphology (FDA-cleared 2025).

• Augmentiqs – AR microscopes integrated with LIS.

• BioView – oncology cell imaging.

• DeepPath – pathology decision support.

• Nucleon AI – QC for whole-slide images.

• Navina Path – structured pathology data.

• Cytoreason (Dx use) – model-based biomarker maps.

• PathoLogica – workflow automation.

• Tissue Dynamics – 3D tissue diagnostics.

• Biotax – tissue classification AI.

• Clarifai Health IL – digital biopsy solutions.

• Celloscope – AI for microscopic patterning.

Strategy Insight: The pathology bottleneck is global; Israeli startups win by combining AI + companion biomarker discovery, securing pharma partnerships.

🧪 Point-of-Care

Diagnostics that move from hospital labs into homes

• Healthy.io – smartphone urinalysis.

• TytoCare – home exams + AI lung sounds.

• Sight Diagnostics – CBC analyzer (OLO).

• PixCell Medical – rapid 5-part CBC.

• DarioHealth – connected glucose/cardiometabolic testing.

• Pulsenmore – home fetal ultrasound.

• HeraMED – home fetal monitoring.

• BioBeat – cuffless BP & vitals.

• CardiacSense – wrist wearable for arrhythmias.

• Neteera – contact-free vitals sensing.

• Check-Cap – X-ray colon capsule.

• Rapid Diagnostic Systems – mobile molecular kits.

• TechnoSTAT – coagulation at bedside.

• EarlySense – continuous monitoring.

• GlucoMe – smart diabetes monitor.

• Eureka Diagnostics – smartphone Dx kits.

Strategy Insight: These startups focus on user experience — devices that patients and parents want to use. That drives adoption.

🧬 Genomics & Biomarkers

Decoding DNA, proteins, and immune signals into actionable insights

• Nucleix – epigenetics LBx.

• C2i Genomics – MRD monitoring.

• OncoHost – proteomic therapy response.

• Geneyx – clinical genomics SaaS.

• Emedgene – variant interpretation (Invitae).

• Sequentify – rapid NGS panels.

• Variantyx IL – rare disease genomics.

• MDClone – synthetic clinical data.

• KaryonDx – IVD development.

• JaxBio – biomarker-focused biotech.

• Senseera – emerging Dx firm.

• Enlivex Therapeutics (Dx arm) – immune biomarkers.

• Fore Biotherapeutics – mutation testing.

• Biolojic Design – antibody biomarker discovery.

• FutureMedix – NGS diagnostics.

• Omicsway – proteomic SaaS.

Strategy Insight: Israel’s genomics ecosystem thrives by turning research assets into SaaS, allowing global labs to validate biomarkers faster.

🦠 Infectious & Breath

From pandemics to precision infection diagnostics

• MeMed – host-response Dx for infection type.

• Scentech Medical – breath-based infectious disease detection.

• Nanoscent – VOC breath analytics.

• Virusight Diagnostic – AI + spectroscopy tests.

• Salignostics – saliva-based testing (SaliStick).

• BATM/Adaltis – molecular Dx kits.

• Novamed – rapid diagnostics manufacturing.

• CaVos Biotech – F6S-listed IVD startup.

• Coltac Therapeutics (Dx arm) – diagnostics-linked programs.

• Sanolla – infrasonic stethoscope Dx.

• Exalens – infection detection startup.

• SmartBreath – handheld breath analyzers.

• MediTect – infection AI diagnostics.

• PathoGenX – multiplex rapid tests.

• COVIDetect IL – PCR replacement kits.

Strategy Insight: These startups excel at turning crises into platforms — pivoting from COVID-19 into broader infectious diagnostics.

👁 Ophthalmic & Vision

Eyes as the new diagnostic frontier

• AEYE Health – autonomous DR screening (FDA).

• Notal Vision – home OCT for AMD.

• NovaSight – pediatric diagnostics (amblyopia).

• 6over6 (GlassesOn) – smartphone refraction testing.

• BioEye – ocular diagnostics via phone.

• AEyeMotion – eye-movement analytics.

• EyeControl – communication & vision tracking.

• Eyeron – retinal analytics.

• SeeTrue / Opheye – early-stage vision AI.

• OpRegen – retinal imaging endpoints.

• OrCam – AI assistive devices with Dx components.

• Ophthorobotics – robotic ophthalmic Dx.

• Retispec – retinal Alzheimer’s detection.

• EyeYon Medical – corneal Dx tools.

Strategy Insight: Israel links ophthalmology + neurology — using the retina as a window to systemic disease.

🌍 Closing Thought

Israel has produced 90+ diagnostics startups that show us the playbook:
👉 Focus on narrow clinical problems.
👉 Use AI or biology to create step-change accuracy.
👉 Scale via global partnerships early.

For health innovators and investors worldwide, this map isn’t just a list — it’s an invitation to rethink how diagnostics should look in 2030.

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